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Invitrogen
LTBR Polyclonal Antibody
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LTBR Antibody (PA5-88290) in WB
Western Blot was performed using Anti-LTBR Polyclonal Antibody (Product # PA5-88290) and a 55 kDa band corresponding to Tumor necrosis factor receptor superfamily member 3 was observed across the cell lines tested except in SH-SY5Y and HEK-293 which are reported to be negative. Whole cell extracts (30 µg lysate) of HeLa (Lane 1), A549 (Lane 2), MCF7 (Lane 3), HUVEC (Lane 4), SH-SY5Y (Lane 5) and HEK-293 (Lane 6) were electrophoresed using NuPAGE™ 10% Bis-Tris Protein Gel (Product # NP0302BOX). Resolved proteins were then transferred onto a... View More
产品信息
PA5-88290
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 249-435 of human LTBR (NP_0023331)
偶联物
形式
Liquid
浓度
0.47 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KSHPSLCRKL GSLLKRRPQG EGPNPVAGSW EPPKAHPYFP DLVQPLLPIS GDVSPVSTGL PAAPVLEAGV PQQQSPLDLT REPQLEPGEQ SQVAHGTNGI HVTGGSMTIT GNIYIYNGPV LGGPPGPGDL PATPEPPYPI PEEGDPGPPG LSTPHQEDGK AWHLAETEHC GATPSNRGPR NQFITHD; Positive Samples: Mouse liver; Cellular Location: Membrane, Single-pass type I membrane protein
靶标信息
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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