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Invitrogen
LZTR2 Polyclonal Antibody
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产品信息
PA5-65853
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human LZTR2
偶联物
形式
Liquid
浓度
0.4 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: SYQSPTMREEY AYGSYYYHGH PQWLQEERVP RQRSPYIWHE DYREQKYLDE HHYENQHSPF GTNSETHFQS NSR
Highest antigen sequence identity to the following orthologs - mouse 62%, rat 62%.
靶标信息
LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene. LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation. Recent evidence has suggested that there is a strong correlation of single nucleotide polymorphisms of LZTR2 with obesity in the Japanese population similar to that seen with the TMEM18 gene and the GNPDA2, BDNF, FAIM2, and MC4R genes with obesity in Caucasian populations, suggesting LZTR2 may play a role in metabolism and obesity risk.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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