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Invitrogen
LZTS2 Polyclonal Antibody
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产品信息
PA5-44945
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the N-terminal of human LZTS2 (aa 71-120).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Peptide sequence: EPLCPAVPPR KAVPVTSFTY INEDFRTESP PSPSSDVEDA REQRAHNAHL
Sequence homology: Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
靶标信息
LZTS2 is a negative regulator of katanin-mediated microtubule severing and release from the centrosome. LZTS2 is required for central spindle formation and the completion of cytokinesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hLZTS2; Leucine zipper putative tumor suppressor 2; leucine zipper, putative tumor suppressor 2; Protein LAPSER1; RP11-108L7.8
基因别名: KIAA1813; LAPSER1; LZTS2
UniProt ID: (Human) Q9BRK4
Entrez Gene ID: (Human) 84445
cytokinesis
kidney development
mitotic nuclear division
negative regulation of cell proliferation
positive regulation of cell death
Wnt signaling pathway
microtubule severing
nuclear export
spindle midzone assembly
negative regulation of canonical Wnt signaling pathway
negative regulation of protein localization to nucleus
