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Invitrogen
Lambda Light Chain Polyclonal Antibody
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产品信息
PA5-16651
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Lambda light chains purified from human Bence Jones proteins
偶联物
形式
Liquid
纯化类型
purified
保存液
PBS, pH 7.4, with 0.2% BSA
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
PA5-16651 targets Lambda Light Chain in IHC (P) applications and shows reactivity with Human, mouse, Non-human primate, and Rat samples.
The PA5-16651 immunogen is lambda light chains purified from human Bence Jones proteins.
靶标信息
Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30. Antibodies to the kappa light chain are reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Bence Jones Protein; BJP; IGL; IGLC 1/2/3; Immunoglobulin L; immunoglobulin lambda light chain; Lambda LC; Mcg Marker; Paraprotein
基因别名: IGLC; IGLV
Entrez Gene ID: (Human) 3537, (Human) 3546
