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Invitrogen
Lamin A/C Monoclonal Antibody (JOL2), HRP
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Lamin A/C Antibody (MA5-46598) in WB
Biology of the cell 2024 -
1 FIGURE Introduction of a DCM-associated point mutation (K97E-LA) of lamin A in C2C12 cells and decrease in repression marker H3K27me3 and Altered H3-specific modified epigenome in DCM-associated mutant lamin A (K97E-LA) transfected C2C12 cells: (a) schematic representation of the position of a DCM-associated point mutation (K97E- Lysine 97Glutamic Acid) on the 1B subunit of alpha helical rod domain in ful... View More
产品信息
MA5-46598
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
JOL2
抗原
Recombinant human lamin A
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
靶标信息
Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. These proteins are found in many different cell types in three different forms (A, B, and C). Lamins A and C are alternatively spliced versions of the LMNA gene. The LMNA gene has been linked to many disorders of the muscular system, nervous system, and the fat distributions systems including: Emery-Dreifuss muscular dystrophy, Dunnigan-type familial partial lipodystrophy (FPLD), limb-girdle muscular dystrophy (LGMD1B), dilated cardiomyopathy (CMD1A), axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1), and mandibuloacral dysplasia (MAD).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
