Progen

Lamin Monoclonal Antibody (X223)

Name: Lamin Monoclonal Antibody (X223)
Brand: Progen
SKU: 61047C

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

产品信息

61047C

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

免疫组化（冰冻） (IHC (F))

1:10

免疫细胞化学 (ICC/IF)

1:10

产品规格

种属反应

Bovine, Fish, Human, Marsupial, Mouse, Rat

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

X223

抗原

Nuclear Pore Complex-Lamina Fraction Of Xenopus Laevis (Xlke-A6 Cells)

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.05 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 0.5% BSA

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitute lyophilized product with 1 mL distilled water.

Recognizes karyoskeleton, i.e. the intermediate filament equivalent of the nucleus. The epitope was localized to coil 1B.

靶标信息

Laminins are high-molecular weight proteins of the extracellular matrix. They are a major component of the basal lamina (one of the layers of the basement membrane), a protein network foundation for most cells and organs. The laminins are an important and biologically active part of the basal lamina, influencing cell differentiation, migration, and adhesion. Laminins are heterotrimeric proteins that contain an alpha-chain, a beta-chain, and a gamma-chain, found in five, four, and three genetic variants, respectively. The laminin molecules are named according to their chain composition. Thus, laminin-511 contains alpha 5, beta 1, and gamma 1 chains. Fourteen other chain combinations have been identified in vivo. The trimeric proteins intersect to form a cross-like structure that can bind to other cell membrane and extracellular matrix molecules. The three shorter arms are particularly good at binding to other laminin molecules, which allows them to form sheets. The long arm is capable of binding to cells, which helps anchor organized tissue cells to the membrane.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: 70 kDa lamin; lamin A; lamin A/C-like 1; lamin B2; lamin B3; lamin C; lamin C2; lamin-A/C; Lamin-B1; Lamin-B2; Prelamin-A/C; renal carcinoma antigen NY-REN-32; unnamed protein product

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基因别名: ADLD; CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; EPM9; FPL; FPLD; FPLD2; HGPS; IDC; LAMB2; LDP1; LFP; LGMD1B; LMN; LMN1; LMN2; LMNA; LMNB; LMNB1; LMNB2; LMNC; LMNL1; PRO1; RGD1563803