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Laminins are large heterotrimeric, noncollagenous glycoproteins composed of alpha, beta, and gamma chains. They are ubiquitously present in basement membrane (BM) along with entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AA408497; Lama; Laminin B1s chain; Laminin B2 chain; Laminin chain B3; laminin chain beta 2; Laminin S; Laminin subunit beta-2; Laminin subunit gamma-1; laminin, beta 2 (laminin S); laminin, gamma 1 (formerly LAMB2); Laminin-1 subunit gamma; Laminin-10 subunit gamma; Laminin-11 subunit beta; Laminin-11 subunit gamma; Laminin-14 subunit beta; Laminin-15 subunit beta; Laminin-2 subunit gamma; Laminin-3 subunit beta; Laminin-3 subunit gamma; Laminin-4 subunit beta; Laminin-4 subunit gamma; Laminin-6 subunit gamma; Laminin-7 subunit beta; Laminin-7 subunit gamma; Laminin-8 subunit gamma; Laminin-9 subunit beta; Laminin-9 subunit gamma; S-LAM beta; S-LAM gamma; S-laminin subunit beta; S-laminin subunit gamma
基因别名: AW211941; B2e; Lamb-2; LAMB2; LAMC1; LAMS; NPHS5; npht; SLAM
UniProt ID: (Human) P55268, (Human) P11047, (Mouse) Q61292, (Rat) P15800
Entrez Gene ID: (Human) 3913, (Human) 3915, (Mouse) 16779, (Rat) 25473, (Mouse) 226519, (Rat) 117036