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Invitrogen
Lefty1/Lefty2 Polyclonal Antibody
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Lefty1/Lefty2 Antibody (PA5-23442) in WB
Western blot analysis of Lefty1/2 in human heart lysate in the 1) absence, 2) presence of immunizing peptide, 3) Mouse and 4) rat heart lysate using a Lefty1, 2 polyclonal antibody (Product # PA5-23442) at 3 ug/ml. Goat anti-rabbit Ig HRP secondary antibody.
产品信息
PA5-23442
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide (244 DYGAQGDCDPEAPMTEGTR 262) of Lefty1/2 protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
This antibody detects both LEFTY1 and LEFTY2, the immunogen sequence is 100% conserved.
靶标信息
Left-right determination factor 1 and 2 (Lefty1/2) belong to the TGF-beta superfamily of proteins and are responsible for determination of left-right positioning of visceral organs during embryogenesis. Lefty1 acts as a regulator of Lefty2 and NODAL as the lack of the former resulted in bilateral expression of nodal, lefty2 and Pitx2 (a homeobox gene normally expressed on the left side and blocks the signal for leftness). Lefty2 may play a role in endometrial bleeding.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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