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Invitrogen
Levodopa Polyclonal Antibody
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Levodopa Antibody (PA5-119575) in ELISA
ELISA of Levodopa in 100 µL (coated at a concentration of 10 µg/mL) of Levodopa carrier protein conjugate. Detection range is 360 ng/mL down to 1.3 ng/mL (coated ligand detection range). Sample was incubated with polyclonal Levodopa antibody (Product # PA5-119575), followed by Rabbit IgG (HRP) with a dilution of 1:2000.
产品信息
PA5-119575
产品规格
种属反应
Chemical
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Levodopa (L-DOPA).
偶联物
形式
Liquid
浓度
0.35 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
靶标信息
Levodopa, also known as L-DOPA, is the most widely used drug for the symptomatic treatment of Parkinson's disease, serving as the gold standard for managing the disease's motor symptoms. It functions as a precursor to dopamine, which is deficient in patients with Parkinson's disease due to the degeneration of dopaminergic neurons in the substantia nigra. Once ingested, levodopa crosses the blood-brain barrier and is converted to dopamine, thereby alleviating symptoms such as bradykinesia, rigidity, and tremor. The pharmacokinetics and pharmacodynamics of levodopa have been extensively studied, with various formulations developed to optimize its absorption and reduce side effects. Despite its efficacy, long-term use of levodopa can lead to complications, including motor fluctuations and dyskinesias.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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