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Invitrogen
Lubricin Polyclonal Antibody
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产品信息
PA3-130
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues I(19) Q Q V S S Q D L S(28)C of human Lubricin.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
PA3-130 detects lubricin in human samples.
PA3-130 has been successfully used in Western blot procedures. By Western blot, this antibody detects a ~64 kDa protein representing lubricin in human samples.
The PA3-130 immunogen is a synthetic peptide corresponding to residues I(19) Q Q V S S Q D L S(28)C of human Lubricin. This polyclonal antibody has been referred to as: JSCIQQ. This peptide (Cat. # PEP-288) is available for use in neutralization and control experiments.
靶标信息
Lubricin is a glycoprotein encoded by the PRG4 gene. It has been identified as a component of joint lubrication and synovial homeostasis by reducing friction in joints and preventing synovial cell overgrowth. It is a large, water soluble molecule that acts as a carrier for insoluble surface-active phospholipid (SAPL). Depletion of lubricin function has been associated with camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP), an arthritic-like autosomal recessive disorder.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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