A synthetic peptide from internal region of mouse MAD3 (Max dimerization protein 3) conjugated to an immunogenic carrier protein was used as the antigen

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

Conc. Not Determined

保存液

whole serum

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Specificity of this antibody: MAD3.

靶标信息

This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: FLJ35523; Max dimerization protein 3; Max dimerizer 3; Max-associated protein 3; Max-interacting transcriptional repressor MAD3; MGC2383; Myx

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基因别名: 4631412E13Rik; bHLHc13; Mad3; Mxd3; Myx

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UniProt ID: (Rat) Q62912, (Mouse) Q80US8

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Entrez Gene ID: (Rat) 252915, (Mouse) 17121

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功能

DNA binding protein dimerization activity protein binding basic helix-loop-helix transcription factor

参与通路

transcription, DNA-templated regulation of transcription, DNA-templated negative regulation of transcription, DNA-templated