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Invitrogen
MAD3 Polyclonal Antibody
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MAD3 Antibody (PA5-102965) in IHC (P)
Immunohistochemistry analysis of MAD3 in human lung cancer and para-carcinoma tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with MAD3 polyclonal antibody (Product # PA5-102965) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-102965
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human MXD3(Accession Q9BW11), corresponding to amino acid residues Q131-G181.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total MXD3.
靶标信息
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bHLHc13; Class C basic helix-loop-helix protein 13; FLJ35523; Max dimerization protein 3; Max dimerizer 3; Max-associated protein 3; Max-interacting transcriptional repressor MAD3; MGC2383; Myx
基因别名: 4631412E13Rik; BHLHC13; MAD3; MXD3
UniProt ID: (Mouse) Q80US8
Entrez Gene ID: (Mouse) 17121
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