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产品信息
PA5-50444
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:1,000-1:5,000 | - |
免疫组化（石蜡） (IHC (P)) |
1:50-1:200 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Fusion protein corresponding to a region derived from internal residues of human melanoma antigen family A, 10 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
2.3 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2635897 |
产品详细信息
The antibody detects endogenous levels of total MAGEA10 protein.
靶标信息
MAGEA10 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.
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生物信息学
蛋白别名: Cancer/testis antigen 1.10; cancer/testis antigen family 1, member 10; CT1.10; MAGE-10 antigen; melanoma antigen family A, 10; melanoma antigen family A10; Melanoma-associated antigen 10
基因别名: CT1.10; MAGE10; MAGEA10
UniProt ID: (Human) P43363
Entrez Gene ID: (Human) 4109
分子生物学功能:
scaffold/adaptor protein
