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Peptide sequence: MSLEQKSQHC KPEEGLDTQE EALGLVGVQA ATTEEQEAVS SSSPLVPGTL
Sequence homology: Human: 100%
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members, and this gene can be alternatively interpreted to be a pseudogene. The protein is represented in this Gene record in accordance with the assumed protein-coding status defined in the literature. Read-through transcription exists between this gene and the upstream melanoma antigen family A, 10 (MAGEA10) gene. [provided by RefSeq, Oct 2011].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: cancer/testis antigen 1.5; cancer/testis antigen family 1, member 5; MAGE-5 antigen; MAGE-5a antigen; MAGE-5b antigen; melanoma antigen family A, 5; melanoma antigen family A5; MGC129526
基因别名: CT1.5; MAGE5; MAGEA4
Entrez Gene ID: (Human) 4104
分子生物学功能:
scaffold/adaptor protein