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Immunogen sequence: RRNARAAEEN RNNRKIQASE ASETPMAASV VASTPEDDLS GPEEDPSTPE EASTTPEEAS STAQAQKPSV PRSNFQGTKK S
Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGEH1 is not fully elucidated, it may play a role in embryonal development and tumor transformation or aspects of tumor progression.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 1-Apr; MAGE-H1 antigen; Melanoma-associated antigen H1
基因别名: 2010107K23Rik; APR-1; APR1; Mageh1
UniProt ID: (Mouse) Q9NWG9
Entrez Gene ID: (Mouse) 75625