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Proteintech
MALT1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
11660-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MALT1 Fusion Protein Ag2182 (125-450 aa encoded by BC030143)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.26 mg/mL
规格
39 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: PGIKITVNP ESKAVLAGQF VKLCCRATGH PFVQYQWFKM NKEIPNGNTS ELIFNAVHVK DAGFYVCRVN NNFTFEFSQW SQLDVCDIPE SFQRSVDGVS ESKLQICVEP TSQKLMPGST LVLQCVAVGS PIPHYQWFKN ELPLTHETKK LYMVPYVDLE HQGTYWCHVY NDRDSQDSKK VEIIIDELNN LGHPDNKEQT TDQPLAKDKV ALLIGNMNYR EHPKLKAPLV DVYELTNLLR QLDFKVVSLL DLTEYEMRNA VDEFLLLLDK GVYGLLYYAG HGYENFGNSF MVPVDAPNPY RSENCLCVQN ILKLMQEKET GLNVFLL (125-450 aa encoded by BC030143 )
靶标信息
MALT1/Paracaspase (MALT1) was independently identified as a member of the human paracaspase family and an interacting partner of B-cell lymphoma (Uren et al., 2000). MALT1 is a caspase-like protein that contains an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain. It binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: caspase-like protein; DKFZp434L132; malt-1; MALT1 protease; MALT1; MLT1; mucosa associated lymphoid tissue lymphoma translocation gene 1; paracaspase-1; unnamed protein product
基因别名: A630046N12; D430033E09Rik; IMD12; MLT; MLT1; PCASP1
UniProt ID: (Human) Q9UDY8, (Mouse) Q2TBA3
Entrez Gene ID: (Human) 10892, (Mouse) 240354, (Rat) 307366
positive regulation of immune effector process
positive regulation of T cell cytokine production
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
proteolysis
defense response
regulation of signal transduction
protein catabolic process
positive regulation of protein ubiquitination
lipopolysaccharide-mediated signaling pathway
positive regulation of interleukin-1 beta production
positive regulation of interleukin-2 production
B cell activation
regulation of apoptotic process
negative regulation of apoptotic process
regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
T cell receptor signaling pathway
nuclear export
positive regulation of multicellular organismal process
cellular response to lipopolysaccharide
positive regulation of T-helper 17 cell differentiation
B-1 B cell differentiation
apoptotic process
I-kappaB kinase/NF-kappaB signaling
response to fungus
T cell proliferation
cell development
regulation of T cell receptor signaling pathway
positive regulation of T cell activation
biological_process
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