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Invitrogen
MALT1 Polyclonal Antibody
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产品信息
PA5149648
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human MALT1
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KVLEPEGSPS LCLLKLMGEK GCTVTELSDF LQAMEHTEVL QLLSPPGIKI TVNPESKAVL AGQFVKLCCR ATGHPFVQYQ WFKMNKEIPN GNTSELIFNA VHVKDAGFYV CRVNNNFTFE FSQWSQLDVC DIPESF
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 79%.
靶标信息
MALT1/Paracaspase (MALT1) was independently identified as a member of the human paracaspase family and an interacting partner of B-cell lymphoma (Uren et al., 2000). MALT1 is a caspase-like protein that contains an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain. It binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: caspase-like protein; DKFZp434L132; MALT lymphoma-associated translocation; malt-1; MALT1 protease; mucosa associated lymphoid tissue lymphoma translocation gene 1; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; Paracaspase; paracaspase 1; paracaspase-1
基因别名: IMD12; MALT1; MLT; MLT1; PCASP1
UniProt ID: (Human) Q9UDY8
Entrez Gene ID: (Human) 10892
B-1 B cell differentiation
stimulatory C-type lectin receptor signaling pathway
response to molecule of bacterial origin
positive regulation of T cell cytokine production
proteolysis
defense response
activation of NF-kappaB-inducing kinase activity
response to fungus
protein ubiquitination
positive regulation of protein ubiquitination
positive regulation of interleukin-2 production
Fc-epsilon receptor signaling pathway
T cell proliferation
regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
T cell receptor signaling pathway
regulation of T cell receptor signaling pathway
positive regulation of T cell activation
positive regulation of NF-kappaB transcription factor activity
nuclear export
protein oligomerization
