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Proteintech
MAN1B1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
15243-1-AP
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MAN1B1 fusion protein Ag7455
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
75 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: LFLRKAEDFG NRLMPAFRTP SKIPYSDVNI GTGVAHPPRW TSDSTVAEVT SIQLEFRELS RLTGDKKFQE AVEKVTQHIH GLSGKKDGLV PMFINTHSGL FTHLGVFTLG ARADSYYEYL LKQWIQGGKQ ETQLLEDYVE AIEGVRTHLL RHSEPSKLTF VGELAHGRFS AKMDHLVCFL PGTLALGVYH GLPASHMELA QELMETCYQM NRQMETGLSP EIVHFNLYPQ PGRRDVEVKP ADRHNLLRPE TVESLFYLYR VTGDRKYQDW GWEILQSFSR FTRVPSGGYS SINNVQDPQK PEPRDKMESF FLGETLKYLF LLFSDDPNLL SLDAYVFNTE AHPLPIWTPA
靶标信息
Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man9GlcNAc2 to produce Man8GlcNAc2, but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man5-6GlcNAc2. Tremblay L.O., Glycobiology 9:1073-1078(1999) [PubMed: 10521544]. Gonzalez D.S., J. Biol. Chem. 274:21375-21386(1999) [PubMed: 10409699]. Clark H.F., Genome Res. 13:2265-2270(2003) [PubMed: 12975309].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 3.2.1.113; endoplasmic Reticulum Class I alpha-mannosidase; endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 1; ER alpha 1,2-mannosidase; Man9GlcNAc2-specific processing alpha-mannosidase; RP11-350O14.2; unnamed protein product
基因别名: ERMAN1; ERManI; MANA-ER; MRT15
UniProt ID: (Human) Q9UKM7
Entrez Gene ID: (Human) 11253
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