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Invitrogen
MAPKAPK3 Polyclonal Antibody
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产品信息
PA1-27830
产品规格
宿主/亚型
Chicken
/ IgY
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to human MAP kinase-activated protein kinase 3.
偶联物
形式
Liquid
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
PA1-27830 detects MAPKAPK3 from human samples.
PA1-27830 may be successfully used in Western blot applications.
The immunogen is a synthetic peptide corresponding to human MAP kinase-activated protein kinase 3.
靶标信息
MAPKAPK3 functions as an integrative element of signaling in both mitogen and stress responses. MAPKAPK3 functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. MAPKAPK3 was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. MAPKAPK3 was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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