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Proteintech
MAT1A Polyclonal Antibody
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产品信息
12395-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Plant,
Rat
已发表种属
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MAT1A Fusion Protein Ag3076 (1-395 aa encoded by BC018359)
偶联物
形式
Liquid
浓度
0.15 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody was raised against the full length of human MAT1A and may cross-react with MAT2A. Western blot analysis using this antibody detected a single band around 44-50kD in liver.
Immunogen sequence: MNGPVDGLC DHSLSEGVFM FTSESVGEGH PDKICDQISD AVLDAHLKQD PNAKVACETV CKTGMVLLCG EITSMAMVDY QRVVRDTIKH IGYDDSAKGF DFKTCNVLVA LEQQSPDIAQ CVHLDRNEED VGAGDQGLMF GYATDETEEC MPLTIILAHK LNARMADLRR SGLLPWLRPD SKTQVTVQYM QDNGAVIPVR IHTIVISVQH NEDITLEEMR RALKEQVIRA VVPAKYLDED TVYHLQPSGR FVIGGPQGDA GVTGRKIIVD TYGGWGAHGG GAFSGKDYTK VDRSAAYAAR WVAKSLVKAG LCRRVLVQVS YAIGVAEPLS ISIFTYGTSQ KTERELLDVV HKNFDLRPGV IVRDLDLKKP IYQKTACYGH FGRSEFPWEV PRKLVF (1-395 aa encoded by B C018359)
靶标信息
MAT1A catalyzes the formation of S-adenosylmethionine from methionine and ATP. Methionine adenosyltransferase deficiency is caused by recessive and dominant mutations, the latter identified in autosomal dominant persistant hypermethioninemia.This gne encodes methionine adenosyltransferase I (alpha isoform), which catalyzes the formation of S-adenosylmethionine from methionine and ATP. Methionine adenosyltransferase deficiency is caused by recessive and dominant mutations, the latter identified in autosomal dominant persistant hypermethioninemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: AdoMet synthase 1; adoMet synthetase 1; MAT 1; MAT-I/III; Methionine adenosyltransferase 1; methionine adenosyltransferase I, alpha; Methionine adenosyltransferase I/III; S - adenosylmethionine synthetase; S-adenosylmethionine synthase isoform type-1; S-adenosylmethionine synthetase isoform type-1
基因别名: AdoMet; AI046368; Ams; AMS1; MAT; MAT1A; MATA1; SADE; SAMS; SAMS1; SAS
UniProt ID: (Human) Q00266, (Rat) P13444, (Mouse) Q91X83
Entrez Gene ID: (Human) 4143, (Rat) 25331, (Mouse) 11720
methionine adenosyltransferase activity
ATP binding
metal ion binding
selenomethionine adenosyltransferase activity
magnesium ion binding
amino acid binding
identical protein binding
protein homodimerization activity
ADP binding
protein dimerization activity
nucleotide binding
transferase activity
nucleotidyltransferase
