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Proteintech
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: AGVGSSPGD QSGDENITQM LKRAHDCRKT AENAAKALLM KLDGSCGGAF AVAGCSVQPW ESLSSNSHTS TTSSTASSCD TEFTKEDEQR LKDYIQQLKN DRAAVKLTML ELESIHIDPL SYDVKPRGDS QRLDLENAVL MQELMAMKEE MAELKAQLYL LEKEKKALEL KLSTREAQEQ AYLVHIEHLK SEVEEQKEQR MRSLSSTSSG SKDKPGKECA DAASPALSLA ELRTTCSENE LAAEFTNAIR REKKLKARVQ ELVSALERLT KSSEIRHQQS AEFVNDLKRA NSNLVAAYEK AKKKHQNKLK KLESQMMAMV ERHETQVRML KQRIALLEEE NSRPHTNETS L (480-829 aa encoded by BC018919)
This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MCC, WNT signaling pathway regulator; mutated in colorectal cancers; unnamed protein product
基因别名: D18Ertd451e; E330037C19; MCC1
UniProt ID: (Human) P23508
Entrez Gene ID: (Human) 4163, (Mouse) 328949