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Proteintech
MCHR1 Polyclonal Antibody
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产品信息
11656-2-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MCHR1 Fusion Protein Ag2224 (1-422 aa encoded by BC021146)
偶联物
形式
Liquid
浓度
0.27 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSVGAMKKG VGRAVGLGGG SGCQATEEDP LPDCGACAPG QGGRRWRLPQ PAWVEGSSAR LWEQATGTGW MDLEASLLPT GPNASNTSDG PDNLTSAGSP PRTGSISYIN IIMPSVFGTI CLLGIIGNST VIFAVVKKSK LHWCNNVPDI FIINLSVVDL LFLLGMPFMI HQLMGNGVWH FGETMCTLIT AMDANSQFTS TYILTAMAID RYLATVHPIS STKFRKPSVA TLVICLLWAL SFISITPVWL YARLIPFPGG AVGCGIRLPN PDTDLYWFTL YQFFLAFALP FVVITAAYVR ILQRMTSSVA PASQRSIRLR TKRVTRTAIA ICLVFFVCWA PYYVLQLTQL SISRPTLTFV YLYNAAISLG YANSCLNPFV YIVLCETFRK RLVLSVKPAA QGQLRAVSNA QTADEERTES KGT (1-422 aa encoded by BC021146)
靶标信息
MCHR1 is a member of the G protein-coupled receptor family 1. It is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G protein coupled receptor 24; G protein-coupled receptor 24; G-protein coupled receptor 24; GPCR24; Gpr24-9 protein coupled receptor; MCH 1 receptor; MCH receptor 1; MCH-1R; MCH-R1; MCH1; MCH1R; MCHR; MCHR-1; Melanin-concentrating hormone receptor 1; SLC-1; Somatostatin receptor-like protein
基因别名: AW049955; GPR24; MCH-1R; MCH1R; MCHR1; SLC-1; SLC1
UniProt ID: (Human) Q99705, (Mouse) Q8JZL2, (Rat) P97639
Entrez Gene ID: (Human) 2847, (Mouse) 207911, (Rat) 83567
generation of precursor metabolites and energy
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
feeding behavior
signal transduction
positive regulation of calcium ion transport
regulation of feeding behavior
