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Invitrogen
MCM2 Monoclonal Antibody (CRCT2.1)
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产品信息
MA5-12333
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
CRCT2.1
抗原
Bacterially expressed human MCM2
偶联物
形式
Liquid
浓度
0.4 mg/mL
规格
200 µg
纯化类型
Protein G
保存液
PBS, pH 7.4, with 0.2% BSA
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA5-12333 targets MCM2 in IHC (P) and WB applications and shows reactivity with Human samples.
The MA5-12333 immunogen is bacterially expressed human MCM2.
靶标信息
MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication. MCM2 (also called CDCL1, mitotin and BM28), is a human nuclear protein that is crucial in the cell cycle, being involved in the onset of DNA replication and cell division. It is similar to members of the family of early S-phase proteins. MCM2 has been mapped to 3q21. From its localization, CDCL1 became a candidate for an oncogene affected by chromosomal breaks in acute myeloid leukemia (AML).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: cell devision cycle-like 1; cyclin-like 1; DNA replication licensing factor MCM2; KIAA0030; MGC10606; minichromosome maintenance deficient 2 (mitotin); Minichromosome maintenance protein 2 homolog; Nuclear protein BM28; unnamed protein product
基因别名: BM28; CCNL1; cdc19; CDCL1; D3S3194; DFNA70; KIAA0030; MCM2; MITOTIN
UniProt ID: (Human) P49736
Entrez Gene ID: (Human) 4171
nucleotide binding
DNA binding
DNA helicase activity
DNA replication origin binding
single-stranded DNA binding
helicase activity
protein binding
ATP binding
zinc ion binding
hydrolase activity
ATPase activity
single-stranded DNA-dependent ATP-dependent DNA helicase activity
enzyme binding
histone binding
3'-5' DNA helicase activity
metal ion binding
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