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Invitrogen
MCT2 Polyclonal Antibody
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MCT2 Antibody (PA5-77498) in IHC (F)
Immunohistochemistry analysis of MCT2 in perfusion-fixed, frozen mouse brain. A) Samples were probed with MCT2 polyclonal antibody (Product # PA5-77498) using a dilution of 1:1000, and incubated with DAPI (green). B) Dorsal pons brain stem regions (red) appears in neuronal outlines.
产品信息
PA5-77498
应用
建议稀释比
已发表文章
产品规格
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide (C)KEMEALSRSKQDD, corresponding to amino acid residues 456-468 of rat Monocarboxylate Transporter 2
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Product is shipped at room temperature as a lyophilized powder and should be stored at -20C upon receipt.
Reconstitute using 50 uL deionized water.
靶标信息
Tissues with few or no mitochondria, such as erythrocytes and tumor cells, depend largely on glycolysis to generate ATP. The major end products of glycolysis, pyruvate and lactate, must be eliminated from these cells to enable continued glycolytic flux and prevent toxic effects. H+/monocarboxylate transporters mediate the transport of lactate and pyruvate. Human MCT2 has a high affinity for the transport of pyruvate.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
