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Invitrogen
MDC Polyclonal Antibody, Biotin, PeproTech®
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MDC Antibody (500-P107BT-25UG) in WB
Western Blot: To detect hMDC by Western Blot analysis MDC Polyclonal Antibody, Biotin (Product # 500-P107BT-500UG) can be used at a concentration of 0.1-0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant hMDC is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
产品信息
500-P107BT-25UG
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived Recombinant Human MDC (CCL22) (69 a.a.)
偶联物
形式
Lyophilized
浓度
0.1-1.0 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
-20°C
运输条件
Ambient
RRID
产品详细信息
AA Sequence of recombinant protein: GPYGANMEDS VCCRDYVRYR LPLRVVKHFY WTSDSCPRPG VVLLTFRDKE ICADPRVPWV KMILNKLSQ.
Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human MDC (CCL22). Anti-Human MDC (CCL22)-specific antibody was purified by affinity chromatography and then biotinylated.
Sandwich ELISA: To detect Human MDC (CCL22) by sandwich ELISA (using 100 µL/well antibody solution) a concentration of 0.25-1.0 µg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human MDC (CCL22) (500-P107) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human MDC (CCL22).
Western Blot: To detect hMDC by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant hMDC is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
500-P107BT-1MG will be provided as 2 x 500 µg
靶标信息
CCL22 may play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Also, it is a chemotactic for monocytes. dendritic cells and natural killer cells. CCL22 is a mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: AW060611; C-C motif chemokine 22; CC chemokine STCP-1; chemokine (C-C motif) ligand 22; Macrophage-derived chemokine; MDC(1-69); MGC108943; MGC34554; RP24-69A20.1; small inducible cytokine A22; small inducible cytokine subfamily A (Cys-Cys), member 22; Small-inducible cytokine A22; stimulated T cell chemotactic protein 1; Stimulated T-cell chemotactic protein 1
基因别名: A-152E5.1; ABCD-1; CCL22; DC/B-CK; MDC; SCYA22; STCP-1
UniProt ID: (Human) O00626
Entrez Gene ID: (Human) 6367
monocyte chemotaxis
chemotaxis
inflammatory response
immune response
signal transduction
G-protein coupled receptor signaling pathway
cell-cell signaling
response to virus
neutrophil chemotaxis
positive regulation of GTPase activity
lymphocyte chemotaxis
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
