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Proteintech
ME2 Polyclonal Antibody
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产品信息
24944-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ME2 Fusion Protein Ag20741 (136-480 aa encoded by BC000147)
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: SISDRGHVR SIVDNWPENH VKAVVVTDGE RILGLGDLGV YGMGIPVGKL CLYTACAGIR PDRCLPVCID VGTDNIALLK DPFYMGLYQK RDRTQQYDDL IDEFMKAITD RYGRNTLIQF EDFGNHNAFR FLRKYREKYC TFNDDIQGTA AVALAGLLAA QKVISKPISE HKILFLGAGE AALGIANLIV MSMVENGLSE QEAQKKIWMF DKYGLLVKGR KAKIDSYQEP FTHSAPESIP DTFEDAVNIL KPSTIIGVAG AGRLFTPDVI RAMASINERP VIFALSNPTA QAECTAEEAY TLTEGRCLFA SGSPFGPVKL TDGRVFTPGQ GNNVYIFPGY RIPIC (136-480 aa encoded by BC000147)
靶标信息
ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: malate dehydrogenase; malate dehydrogenase (oxaloacetate-decarboxylating); Malic enzyme 2; malic enzyme 2, NAD(+)-dependent, mitochondrial; NAD-dependent malic enzyme, mitochondrial; NAD-ME; pyruvic-malic carboxylase
基因别名: ME2; ODS1
UniProt ID: (Human) P23368
Entrez Gene ID: (Human) 4200
