Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
MED17 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
11505-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MED17 Fusion Protein Ag2057 (296-651 aa encoded by BC021101)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: EAAQNVLLC KEIFAQLSRE AVQIKSQVPH IVVKNQIISQ PFPSLQLSIS LCHSSNDKKS QKFATEKQCP EDHLYVLEHN LHLLIREFHK QTLSSIMMPH PASAPFGHKR MRLSGPQAFD KNEINSLQSS EGLLEKIIKQ AKHIFLRSRA AATIDSLASR IEDPQIQAHW SNINDVYESS VKVLITSQGY EQICKSIQLQ LNIGVEQIRV VHRDGRVITL SYQEQELQDF LLSQMSQHQV HAVQQLAKVM GWQVLSFSNH VGLGPIESIG NASAITVASP SGDYAISVRN GPESGSKIMV QFPRNQCKDL PKSDVLQDNK WSHLRGPFKE VQWNKMEGRN FVYKMELLMS ALSPCLL (296-651 aa encoded by BC021101 )
靶标信息
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e. g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Activator-recruited cofactor 77 kDa component; ARC77; Cofactor required for Sp1 transcriptional activation subunit 6; cofactor required for Sp1 transcriptional activation, subunit 6; cofactor required for Sp1 transcriptional activation, subunit 6 (77kD); cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa; CRSP complex subunit 6; DRIP80; Mediator complex subunit 17; Mediator of RNA polymerase II transcription subunit 17; Thyroid hormone receptor-associated protein complex 80 kDa component; Transcriptional coactivator CRSP77; Trap80; Vitamin D3 receptor-interacting protein complex 80 kDa component
基因别名: 77kDa; ARC77; C330002H14Rik; CRSP6; CRSP77; DRIP77; DRIP80; MED17; TRAP80
UniProt ID: (Human) Q9NVC6, (Mouse) Q8VCD5
Entrez Gene ID: (Human) 9440, (Rat) 300367, (Mouse) 234959
RNA polymerase II transcription cofactor activity
transcription cofactor activity
transcription coactivator activity
receptor activity
protein binding
ligand-dependent nuclear receptor transcription coactivator activity
vitamin D receptor binding
thyroid hormone receptor binding
ubiquitin protein ligase activity
general transcription factor
RNA metabolism protein
nucleic acid metabolism protein
regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
protein ubiquitination
stem cell population maintenance
intracellular steroid hormone receptor signaling pathway
androgen receptor signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
