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Invitrogen
MED27 Polyclonal Antibody
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产品信息
PA5-101981
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human MED27(Accession Q6P2C8), corresponding to amino acid residues H120-D170.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total MED27.
靶标信息
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cofactor required for Sp1 transcriptional activation subunit 8; cofactor required for Sp1 transcriptional activation, subunit 8; cofactor required for Sp1 transcriptional activation, subunit 8, 34kDa; CRSP complex subunit 8; Mediator complex subunit 27; Mediator of RNA polymerase II transcription subunit 27; MGC11274; P37 TRAP/SMCC/PC2 subunit; transcriptional co-activator CRSP8 homolog; Transcriptional coactivator CRSP34
基因别名: 1500015J03Rik; 2310042P07Rik; AA682045; CRAP34; CRSP34; CRSP8; D2Ertd434e; MED27; MED3; TRAP37
UniProt ID: (Human) Q6P2C8, (Mouse) Q78JI3
Entrez Gene ID: (Human) 9442, (Mouse) 68975
