This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: QQHQALQTNW HLPQMSSPPS AARHSLCLQP DSGGPPELGS SPPVLCSNSS SLGSSTPTGA ACAPGDYGRQ ALSPAEAEKR SGGKR
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 96%.
Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
蛋白别名: Growth arrest-specific homeobox; Homeobox protein MOX-2; Mesenchyme homeobox 2
基因别名: GAX; MEOX2; MOX2
UniProt ID: (Human) P50222
Entrez Gene ID: (Human) 4223
分子生物学功能: homeodomain transcription factor