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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
0.1-0.5 µg/mL | - |
免疫细胞化学 (ICC/IF) |
2 µg/mL | - |
酶联免疫吸附实验 (ELISA) |
0.1-0.5 µg/mL | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
E.coli-derived human METTL3 recombinant protein (Position: Q423-D571). |
偶联物 |
Unconjugated |
形式 |
Lyophilized |
浓度 |
500 µg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS with 4mg trehalose |
内含物 |
0.05mg sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2807371 |
Reconstitution information: Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
METTL3 is the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: adoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase; hMETTL3; m6a methyltransferase; methyltransferase-like 3; Methyltransferase-like protein 3; mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase; mRNA m(6)A methyltransferase; MT-A70; N6-adenosine-methyltransferase 70 kDa subunit; N6-adenosine-methyltransferase catalytic subunit; N6-adenosine-methyltransferase subunit METTL3
基因别名: 2310024F18Rik; IME4; M6A; METTL3; MT-A70; MTA70; Spo8
UniProt ID: (Human) Q86U44, (Mouse) Q8C3P7
Entrez Gene ID: (Human) 56339, (Mouse) 56335, (Rat) 361035
分子生物学功能:
RNA metabolism protein
RNA methyltransferase
nucleic acid metabolism protein
