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Invitrogen
MGARP Polyclonal Antibody
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
产品信息
PA5-64966
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化（石蜡） (IHC (P)) |
1:2,500-1:5,000 | - |
免疫细胞化学 (ICC/IF) |
0.25-2 µg/mL | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant Human MGARP |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.3 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.2, with 40% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2664184 |
产品详细信息
Immunogen sequence: YKTVTSDQAKH TEHKTNLKEK TKAEIHPFQG EKENVAETEK ASSEAPEELI VEAEVVDAEE SPSATVVVIK EASACPGHVE AAPETTAVSA ETGPEVTDAA A
Highest antigen sequence identity to the following orthologs - mouse 44%, rat 45%.
靶标信息
MGARP plays a role in the trafficking of mitochondria along microtubules. It regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. It participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. It also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CESP-1; Corneal endothelium-specific protein 1; Hypoxia up-regulated mitochondrial movement regulator protein; Mitochondria-localized glutamic acid-rich protein; Ovary-specific acidic protein; Protein MGARP
基因别名: C4orf49; CESP-1; CESP1; GS3582; HUMMR; MGARP; OSAP
UniProt ID: (Human) Q8TDB4
Entrez Gene ID: (Human) 84709
protein targeting to mitochondrion
anterograde axonal transport
retrograde axonal transport
regulation of mitochondrion organization
positive regulation of mitochondrion organization
axonal transport of mitochondrion
cellular response to steroid hormone stimulus
cellular response to hypoxia
cellular response to gonadotropin-releasing hormone
