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Proteintech
MGAT5B Polyclonal Antibody
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产品信息
16993-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MGAT5B Fusion Protein Ag10678 (1-394 aa encoded by BC062354)
偶联物
形式
Liquid
浓度
0.28 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MITVNPDGK IMVRRCLVTL RPFRLFVLGI GFFTLCFLMT SLGGQFSARR LGDSPFTIRT EVMGGPESRG VLRKMSDLLE LMVKRMDALA RLENSSELHR AGGDLHFPAD RMPPGAGLME RIQAIAQNVS DIAVKVDQIL RHSLLLHSKV SEGRRDQCEA PSDPKFPDCS GKVEWMRARW TSDPCYAFFG VDGTECSFLI YLSEVEWFCP PLPWRNQTAA QRAPKPLPKV QAVFRSNLSH LLDLMGSGKE SLIFMKKRTK RLTAQWALAA QRLAQKLGAT QRDQKQILVH IGFLTEESGD VFSPRVLKGG PLGEMVQWAD ILTALYVLGH GLRVTVSLKE LQRQRRLRSS QEQARCGVMG ACEKMLLEGD VASNTLLIEK PSKKETEKCP KNLVT (1-394 aa encoded by BC062354)
靶标信息
Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAcbeta1,2-Manalpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAcbeta1,2-Manalpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B; Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B; beta(1,6)-N-acetylglucosaminyltransferase V; beta1,6-N-acetylglucosaminyltransferase IX (GnT-IX); GlcNAc-T Vb; GNT-IX; GNT-Vb; hGnTVb; mannoside acetylglucosaminyltransferase 5, isoenzyme B; Mannoside acetylglucosaminyltransferase 5B; mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isoenzyme B; N-acetylglucosaminyl-transferase Vb; N-acetylglucosaminyltranferase VB; N-acetylglucosaminyltransferase IX; UDP-N-acetylglucosamine: alpha1,6-D-mannoside beta1,6-N-acetylglucosaminyltransferase b
基因别名: C330018B01; GnT-IX; GnT-VB; KIAA2008; MGAT5B; mGnTVB
UniProt ID: (Human) Q3V5L5, (Mouse) Q765H6
Entrez Gene ID: (Human) 146664, (Rat) 303693, (Mouse) 268510
protein binding
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity
metal ion binding
alpha-1,6-mannosyltransferase activity
alpha-1,2-mannosyltransferase activity
mannosyltransferase activity
alpha-1,3-mannosyltransferase activity
alpha-1,3-galactosyltransferase activity
UDP-glucose:glycoprotein glucosyltransferase activity
glycolipid mannosyltransferase activity
oligosaccharyl transferase activity
dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity
acetylglucosaminyltransferase activity
acetylgalactosaminyltransferase activity
galactosyltransferase activity
fucosyltransferase activity
O antigen polymerase activity
lipopolysaccharide-1,6-galactosyltransferase activity
transferase activity
transferase activity, transferring glycosyl groups
cellulose synthase activity
9-phenanthrol UDP-glucuronosyltransferase activity
1-phenanthrol glycosyltransferase activity
9-phenanthrol glycosyltransferase activity
1,2-dihydroxy-phenanthrene glycosyltransferase activity
phenanthrol glycosyltransferase activity
beta-1,4-mannosyltransferase activity
alpha-1,2-galactosyltransferase activity
dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity
lipopolysaccharide-1,5-galactosyltransferase activity
dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity
dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity
inositol phosphoceramide synthase activity
glucosyltransferase activity
alpha-(1->3)-fucosyltransferase activity
alpha-(1->6)-fucosyltransferase activity
indole-3-butyrate beta-glucosyltransferase activity
salicylic acid glucosyltransferase (ester-forming) activity
salicylic acid glucosyltransferase (glucoside-forming) activity
benzoic acid glucosyltransferase activity
chondroitin hydrolase activity
dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity
cytokinin 9-beta-glucosyltransferase activity
glycosyltransferase
