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Immunogen sequence: RTKRLTAQWAL AAQRLAQKLG ATQRDQKQIL VHIGFLTEES GDVFSPRVLK GGPLGEMVQW ADILTALYVL GHGLRVTVSL KELQSNLGVP PGRGSCPLTM PLPFDLIYTD YHGLQQMKRH MGLSFKKYRC RIRVID
Highest antigen sequence identity to the following orthologs - mouse 89%, rat 88%.
Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAcbeta1,2-Manalpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAcbeta1,2-Manalpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B; Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B; beta(1,6)-N-acetylglucosaminyltransferase V; GlcNAc-T Vb; GNT-IX; GNT-Vb; hGnTVb; Mannoside acetylglucosaminyltransferase 5B; mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isoenzyme B; N-acetylglucosaminyl-transferase Vb; N-acetylglucosaminyltransferase IX
基因别名: GnT-IX; GnT-VB; KIAA2008; MGAT5B
UniProt ID: (Human) Q3V5L5
Entrez Gene ID: (Human) 146664
分子生物学功能:
glycosyltransferase