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Product Details
PA5-61968
Applications
Tested Dilution
Publications
产品规格
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
Immunogen
Recombinant protein corresponding to Human MIDN
Conjugate
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2643968
Product Specific Information
Immunogen sequence: LNDLLSATRH YQGMPPSLAQ LRCHAQCSPA SPAPDLAPRT TSCEKLTAAP SASLLQGQSQ IRMCKPPGDR LRQTENRATR CKVER
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 88%.
Target Information
Expression of the midnolin gene is developmentally regulated: it is strongly expressed at the mesencephalon (midbrain) of the embryo in day 12.5 (E12.5) mice. The midnolin encodes a protein of 508 amino acids (aa), which contains a Ubiquitin-like domain. The intracellular distribution of the midnolin was studied by using midnolin-green fluorescent protein (GFP) fusion proteins. Midnolin was found to be localized in the nucleus and nucleolus, but not in the cytoplasm. The nucleolar localization signal was determined to be a 28aa peptide located at the C-terminal region of the midnolin. May be involved in regulation of genes related to neurogenesis in the nucleolus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: DKFZp547M072; Midbrain nucleolar protein; Midnolin
Gene Aliases: MIDN
UniProt ID: (Human) Q504T8
Entrez Gene ID: (Human) 90007
Performance Guarantee
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