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Proteintech
MINK1 Polyclonal Antibody
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产品信息
13137-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MINK1 Fusion Protein Ag3795 (1-304 aa encoded by BC034673)
偶联物
形式
Liquid
浓度
0.14 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MGDPAPARS LDDIDLSALR DPAGIFELVE VVGNGTYGQV YKGRHVKTGQ LAAIKVMDVT EDEEEEIKQE INMLKKYSHH RNIATYYGAF IKKSPPGNDD QLWLVMEFCG AGSVTDLVKN TKGNALKEDC IAYICREILR GLAHLHAHKV IHRDIKGQNV LLTENAEVKL VDFGVSAQLD RTVGRRNTFI GTPYWMAPEV IACDENPDAT YDYRSDIWSL GITAIEMAEG APPLCDMHPM RALFLIPRNP PPRLKSKKWS KKFIDFIDTC LIKTYLSRPP TEQLLKFPFI RDQPTERQVR IQLKD (1-304 aa encoded by BC034673)
靶标信息
MINK1 is a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: FLJ18426; FLJ38123; FLJ94103; GCK family kinase MINK; hMINK; hMINKbeta; ISK; JLNS; JLNS2; LQT2/5; LQT5; MAPK/ERK kinase kinase kinase 6; MEK kinase kinase 6; MEKKK 6; MGC33114; Mink 1; Mink 2; mink1; Misshapen-like kinase 1; Misshapen/NIK-related kinase; Misshapen/NIKs-related kinase; Mitogen-activated protein kinase kinase kinase kinase 6; Yeast Sps1/Ste20-related kinase 2
基因别名: B55; MAP4K6; MEKKK 6; MINK; MINK1; YSK2; ZC3
UniProt ID: (Human) Q8N4C8, (Mouse) Q9JM52
Entrez Gene ID: (Human) 50488, (Mouse) 50932, (Rat) 303259
protein kinase activity
protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
protein binding
ATP binding
nucleotide binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
regulation of cell-matrix adhesion
protein phosphorylation
response to stress
JNK cascade
chemical synaptic transmission
multicellular organism development
regulation of cell-cell adhesion
microvillus assembly
regulation of cell migration
actin cytoskeleton reorganization
intracellular signal transduction
positive regulation of JNK cascade
protein autophosphorylation
dendrite morphogenesis
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
MAPK cascade
regulation of mitotic cell cycle
phosphorylation
stress-activated protein kinase signaling cascade
activation of protein kinase activity
regulation of apoptotic process
negative thymic T cell selection
neuron projection morphogenesis
neuron cellular homeostasis
signal transduction by protein phosphorylation
regulation of catalytic activity
