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Proteintech
MIOS Recombinant Rabbit Monoclonal Antibody (240832B9)
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产品信息
83856-5-RR
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
240832B9
抗原
MIOS fusion protein Ag15148
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: AVALFNLDIR RAIQILNEGA SSEKGDLNLN VVAMALSGYT DEKNSLWREM CSTLRLQLNN PYLCVMFAFL TSETGSYDGV LYENKVAVRD RVAFACKFLS DTQLNRYIEK LTNEMKEAGN LEGILLTGLT KDGVDLMESY VDRTGDVQTA SYCMLQGSPL DVLKDERVQY WIENYRNLLD AWRFWHKRAE FDIHRSKLDP SSKPLAQVFV SCNFCGKSIS YSCSAVPHQG RGFSQYGVSG SPTKSKVTSC PGCRKPLPRC ALCLINMGTP VSSCPGGTKS DEKVDLSKDK KLAQFNNWFT WCHNCRHGGH AGHMLSWFRD HAECPVSACT CKCMQLDTTG NLVPAETVQP
靶标信息
As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
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生物信息学
蛋白别名: FLJ20323; GATOR2 complex protein MIOS; H_DJ1159O04.1; Missing oocyte meiosis regulator homolog; missing oocyte, meiosis regulator, homolog; WD repeat-containing protein mio; WUGSC:H_DJ1159O04.1
基因别名: C81488; MIO; MIOS; Sea4
UniProt ID: (Human) Q9NXC5, (Mouse) Q8VE19
Entrez Gene ID: (Human) 54468, (Mouse) 252875
