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Proteintech
MKS1 Monoclonal Antibody (6A8B11)
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产品信息
66518-1-IG
产品规格
种属反应
Human,
Pig,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
6A8B11
抗原
MKS1 Fusion Protein Ag9504 (1-321 aa encoded by BC010061)
偶联物
形式
Liquid
浓度
0.9 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MTTAASEVP SFLVERMANV RRRRQDRRGM EGGILKSRIV TWEPSEEFVR NNHVINTPLQ TMHIMADLGP YKKLGYKKYE HVLCTLKVDS NGVITVKPDF TGLKGPYRIE TEGEKQELWK YTIDNVSPHA QPEEEERERR VFKDLYGRHK EYLSSLVGTD FEMTVPGALR LFVNGEVVSA QGYEYDNLYV HFFVELPTAH WSSPAFQQLS GVTQTCTTKS LAMDKVAHFS YPFTFEAFFL HEDESSDALP EWPVLYCEVL SLDFWQRYRV EGYGAVVLPA TPGSHTLTVS TWRPVELGTV AELRRFFIGG SLELEDLSYV RI (1-321 aa encoded by BC010061)
靶标信息
The protein encoded by this gene localizes to the basal body and is required for formation of the primary cilium in ciliated epithelial cells. Mutations in this gene result in Meckel syndrome type 1 and in Bardet-Biedl syndrome type 13. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Meckel syndrome type 1 protein; Meckel syndrome type 1 protein homolog; Meckel syndrome, type 1; POC12 centriolar protein homolog; Tectonic-like complex member MKS1
基因别名: BBS13; MES; MKS; MKS1; POC12
UniProt ID: (Human) Q9NXB0, (Rat) Q499Q5
Entrez Gene ID: (Human) 54903, (Pig) 100514538, (Rat) 287612
neural tube closure
determination of left/right symmetry
epithelial structure maintenance
nonmotile primary cilium assembly
cilium assembly
embryonic digit morphogenesis
embryonic skeletal system development
branching morphogenesis of an epithelial tube
inner ear receptor stereocilium organization
cilium morphogenesis
head development
regulation of canonical Wnt signaling pathway
common bile duct development
regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
motile primary cilium assembly
embryonic brain development
regulation of Wnt signaling pathway, planar cell polarity pathway
regulation of smoothened signaling pathway
motile cilium assembly
