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OriGene
MKX Monoclonal Antibody (OTI6B9), TrueMAB™
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MKX Antibody (CF808429) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MKX (RC206923, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-MKX. (1:2. Positive lysates LY406487 (100 µg) and LC406487 (20 µg) can be purchased separately from OriGene.
产品信息
CF808429
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
OTI6B9
抗原
Full length human recombinant protein of human MKX produced in E.coli.
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
MKX is a member of an Iroquois (IRX) family-related class of 'three-amino acid loop extension' (TALE) atypical homeobox proteins characterized by 3 additional amino acids in the loop region between helix I and helix II of the homeodomain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Homeobox protein Mohawk; Iroquois family related homeodomain protein; iroquois homeobox protein-like 1; mohawk homeobox
基因别名: 9430023B20Rik; C10orf48; IFRX; IRXL1; MKX; RGD1305652
UniProt ID: (Human) Q8IYA7, (Mouse) Q8BIA3
Entrez Gene ID: (Human) 283078, (Mouse) 210719, (Rat) 291228
sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
DNA binding
protein binding
homeodomain transcription factor
regulation of transcription, DNA-templated
muscle organ development
negative regulation of transcription from RNA polymerase II promoter
tendon sheath development
transcription from RNA polymerase II promoter
multicellular organism development
regulation of gene expression
positive regulation of gene expression
collagen fibril organization
positive regulation of collagen biosynthetic process
tendon cell differentiation
tendon formation
negative regulation of myoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
