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Proteintech
MLXIPL Polyclonal Antibody
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产品信息
13256-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MLXIPL Fusion Protein Ag3481 (1-350 aa encoded by BC012925)
偶联物
形式
Liquid
浓度
0.28 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MAGALAGLA AGLQVPRVAP SPDSDSDTDS EDPSLRRSAG GLLRSQVIHS GHFMVSSPHS DSLPRRRDQE GSVGPSDFGP RSIDPTLTRL FECLSLAYSG KLVSPKWKNF KGLKLLCRDK IRLNNAIWRA WYIQYVKRRK SPVCGFVTPL QGPEADAHRK PEAVVLEGNY WKRRIELPPE DAYVGNADMI QPDLTPLQPS LDDFMDISDF FTNSRLPQPP MPSNFPEPPS FSPVVDSLFS SGTLGPEVPP ASSAMTHLSG HSRLQARNSC PGPLDSSAFL SSDFLLPEDP KPRLPPPPVP PPLLHYPPPA KVPGLEPCPP PPFPPMAPPT ALLQEEPLFS PRFPFPTVPP A (1-350 aa encoded by BC012925)
靶标信息
ChREBP is a transcription factor involved in activating genes that encode enzymes of fatty acid biosynthesis in liver and adipose. This protein may have relevance to lipid metabolism, obesity, and type II diabetes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: bHLHd14; carbohydrate response element binding protein; Carbohydrate-responsive element-binding protein; ChREBP; Class D basic helix-loop-helix protein 14; MLX interacting protein-like; MLX interactor; MLX-interacting protein-like; Williams Beuren syndrome chromosome region 14; Williams-Beuren syndrome chromosomal region 14 protein; Williams-Beuren syndrome chromosome region 14 protein 1; Williams-Beuren syndrome chromosome region 14 protein 2; Williams-Beuren syndrome chromosome region 14 protein 3; WS basic-helix-loop-helix leucine zipper protein; WS-bHLH
基因别名: BHLHD14; CHREBP; MIO; MLXIPL; MONDOB; WBSCR14; WS-bHLH
UniProt ID: (Human) Q9NP71
Entrez Gene ID: (Human) 51085
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
carbohydrate response element binding
protein homodimerization activity
protein heterodimerization activity
DNA-binding transcription factor
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
positive regulation of cell proliferation
anatomical structure morphogenesis
glucose mediated signaling pathway
negative regulation of peptidyl-serine phosphorylation
intracellular signal transduction
glucose homeostasis
positive regulation of fatty acid biosynthetic process
positive regulation of glycolytic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of lipid biosynthetic process
fatty acid homeostasis
triglyceride homeostasis
negative regulation of cell cycle arrest
cellular response to carbohydrate stimulus
negative regulation of oxidative phosphorylation
regulation of energy homeostasis
