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Invitrogen
MMP1 Monoclonal Antibody (F15 P3 B6)
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产品信息
MA1-771
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
F15 P3 B6
抗原
Synthetic peptide corresponding to residues C(366) S S F G F P R T V K H(376) of human MMP-1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 1mg/mL BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA1-771 contains 100 µg of in vitro produced, protein A purified antibody (1 mg/mL) in PBS containing 1 mg/mL BSA and 0.05% sodium azide.
MA1-771 detects MMP-1 from human samples.
MA1-771 has been successfully used in Western blot applications. By Western blot, MA1-771 detects a ~50 kDa band representing MMP-1 from A431 and K562 cell lysates.
The MA1-771 immunogen is a synthetic peptide corresponding to residues C(366) S S F G F P R T V K H(376) of human MMP-1.
靶标信息
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Collagenase; Fibroblast collagenase; Interstitial collagenase; matrix metallo protease; matrix metallopeptidase 1 (interstitial collagenase); matrix metalloprotease 1; matrix metalloproteinase 1; Matrix metalloproteinase-1; Matrix metalloproteinase1; MMP; MMP-1; MMPs
基因别名: CLG; CLGN; MMP1
UniProt ID: (Human) P03956
Entrez Gene ID: (Human) 4312
