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OriGene
MMP11 Monoclonal Antibody (OTI2D7), TrueMAB™
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MMP11 Antibody (CF812650) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMP11 (RC209223, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-MMP11. Positive lysates LY416967 (100 µg) and LC416967 (20 µg) can be purchased separately from OriGene.
产品信息
CF812650
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI2D7
抗原
Human recombinant protein fragment corresponding to amino acids 239-488 of human MMP11 produced in E.coli.
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
Stromelysin, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen. The stromelysin-3 (MMP-11) gene was originally identified on the basis that it is expressed specifically in stromal cells surrounding invasive breast carcinomas. MMP-11 is localized by in situ hybridization to the long arm of chromosome 22. The MMP-11 expression is found more specifically in malignant tumors than in benign ones.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: matrix metallo protease; matrix metallopeptidase 11 (stromelysin 3); Matrix metalloproteinase-11; MMP; MMP-11; MMPs; SL-3; stromelysin III; Stromelysin-3
基因别名: MMP11; SL-3; ST3; STMY3
UniProt ID: (Human) P24347
Entrez Gene ID: (Human) 4320
