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This antibody detects endogenous protein at a molecular weight of 37 and 44 kDa.
Purity is >95% by SDS-PAGE.
Matrix metalloproteinases (MMPs) are highly homologous Zn2+ endopeptidases involved in extracellular matrix breakdown. MMP mediated extracellular remodeling occurs in normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, including arthritis and metastasis. MMP-23 exhibits sequence similarity with most MMPs, but displays a difference in domain structure. The MMP-23 protein contains prepro-, catalytic, cysteine-rich, Interleukin-1 receptor-related and proline-rich domains. Lacking a recognizable signal sequence, MMP-23 has a short prodomain. In addition, MMP-23 contains a single cysteine residue that can be part of the cysteine-switch mechanism operation for maintaining enzyme latency. MMP-23 is a membrane-anchored glycoprotein with type II topology. Subcellular localization is predominantly perinuclear.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Femalysin; matrix metalloproteinase 22; matrix metalloproteinase 23B; matrix metalloproteinase in the female reproductive tract; Matrix metalloproteinase-21; Matrix metalloproteinase-22; Matrix metalloproteinase-23; Matrix metalloproteinase-23, soluble form; MIFR-1; MMP 23; MMP-21; MMP-22; MMP-23; MMP23; soluble form
基因别名: MIFR; MIFR-1; MMP21; MMP22; MMP23A; MMP23B
UniProt ID: (Human) O75900
Entrez Gene ID: (Human) 8511, (Human) 8510
分子生物学功能: metalloprotease