Proteintech

MMP3 Monoclonal Antibody (1F5A9)

Name: MMP3 Monoclonal Antibody (1F5A9)
Brand: Proteintech
SKU: 66338-1-IG

35 篇参考文献

查看其他33个MMP3抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (13)

MMP3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 13

MMP3 Antibody (66338-1-IG) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using (Product # 66338-1-IG) (MMP3 antibody) at dilution of 1:4,000 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Immunogen image

Immunogen Image MMP3 Monoclonal Antibody (1F5A9)

产品信息

66338-1-IG

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:2,000-1:10,000

查看25篇已发表文章 25篇已发表文章

免疫组化 (IHC)

查看5篇已发表文章 5篇已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:500

免疫细胞化学 (ICC/IF)

查看5篇已发表文章 5篇已发表文章

产品规格

种属反应

Human, Mouse, Pig, Rat

已发表种属

Human, Mouse

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

1F5A9

抗原

MMP3 Fusion Protein Ag12359 (26-477 aa encoded by BC074869)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: GEDTSMNLV QKYLENYYDL EKDVKQFVRR KDSGPVVKKI REMQKFLGLE VTGKLDSDTL EVMRKPRCGV PDVGHFRTFP GIPKWRKTHL TYRIVNYTPD LPKDAVDSAV EKALKVWEEV TPLTFSRLYE GEADIMISFA VREHGDFYPF DGPGNVLAHA YAPGPGINGD AHFDDDEQWT KDTTGTNLFL VAAHEIGHSL GLFHSANTEA LMYPLYHSLT DLTRFRLSQD DINGIQSLYG PPPDSPETPL VPTEPVPPEP GTPANCDPAL SFDAVSTLRG EILIFKDRHF WRKSLRKLEP ELHLISSFWP SLPSGVDAAY EVTSKDLVFI FKGNQFWAIR GNEVRAGYPR GIHTLGFPPT VRKIDAAISD KEKNKTYFFV EDKYWRFDEK RNSMEPGFPK QIAEDFPGID SKIDAVFEEF GFFYFFTGSS QLEFDPNAKK VTHTLKSNSW LNC (26-477 aa encoded by BC074869)

靶标信息

MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted in its pro-protein form, and is activated by extracellular proteinase cleavage. MMP3 is capable of binding to zinc and calcium ions, and has metallo-endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin. It is involved in normal cellular processes such as wound repair and tissue remodeling. Mutations in the gene can result in coronary heart disease 6.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: EC 3.4.24.17; EMS-2; matrix metallo protease; matrix metallopeptidase 3 (stromelysin 1, progelatinase); matrix metalloproteinase 3; matrix metalloproteinase 3 (stromelysin 1, progelatinase); Matrix metalloproteinase-3; MMP; MMP-3; MMPs; progelatinase; proteoglycanase; SL-1; stromelysin; stromelysin 1; Stromelysin-1; Stromelysin1; Transin-1; Transin1

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基因别名: CHDS6; MMP-3; MMP10; MMP3; SL-1; SLN-1; SLN1; STMY; STMY1; STR-1; STR1

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UniProt ID: (Human) P08254, (Mouse) P28862

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Entrez Gene ID: (Pig) 396769, (Human) 4314, (Mouse) 17392, (Rat) 171045

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功能