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Invitrogen
MOK Polyclonal Antibody
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MOK Antibody (PA5-95928) in IHC (P)
Immunohistochemistry analysis of MOK in paraffin-embedded mouse kidney. Samples were incubated with MOK Polyclonal antibody (Product # PA5-95928) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-95928
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human MOK (NP_0550411)
偶联物
形式
Liquid
浓度
0.47 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MKNYKAIGKI GEGTFSEVMK MQSLRDGNYY ACKQMKQRFE SIEQVNNLRE IQALRRLNPH PNILMLHEVV FDRKSGSLAL ICELMDMNIY ELIRGRRYPL SEKKIMHYMY QLCKSLDHIH RNGIFHRDVK PENILIKQDV LKLGDFGSCR SVYSKQPYTE YISTRWYRAP ECLLTDGFYT YKMDLWSAGC VFYEIASLQP LFPGVNELDQ ISKIHDVIGT PAQKILTKFK; Positive Samples: Mouse liver; Cellular Location: Cytoplasm
靶标信息
MOK is able to phosphorylate several exogenous substrates and to undergo autophosphorylation. It negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MAPK/MAK/MRK overlapping kinase; MAPK/MAK/MRK/ overlapping kinase; MOK protein kinase; RAGE-1; renal cell carcinoma antigen; renal tumor antigen; Renal tumor antigen 1; Serine/threonine kinase 30; soluble RAGE; T/STK 30
基因别名: MOK; RAGE; RAGE-1; RAGE1; STK30
UniProt ID: (Human) Q9UQ07, (Mouse) Q9WVS4
Entrez Gene ID: (Human) 5891, (Rat) 362787, (Mouse) 26448
protein kinase activity
protein serine/threonine kinase activity
cyclin-dependent protein serine/threonine kinase activity
ATP binding
molecular_function
nucleotide binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
