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Invitrogen
MRGD Polyclonal Antibody
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产品信息
PA1-32863
产品规格
种属反应
Human,
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human MRGPRD.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
PA1-32863 detects GPCR LS195564 from human samples.
靶标信息
May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i). Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Beta-alanine receptor; G-protein coupled receptor TGR7; mas-related G protein-coupled MRGD; Mas-related G-protein coupled receptor member D; MAS-related GPR, member D
基因别名: MRGD; MRGPRD; TGR7
UniProt ID: (Human) Q8TDS7
Entrez Gene ID: (Human) 116512
