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Proteintech
MRGPRD Polyclonal Antibody
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产品信息
23640-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MRGPRD fusion protein Ag20316
偶联物
形式
Liquid
浓度
0.85 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: FLICSLPLSI YWFVLYWLSL PPEMQVLCFS LSRLSSSVSS SANPVIYFLV GSRRSHRLPT RSLGTVLQQA LREEPELEGG ETPTVGTNEM GA
靶标信息
May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i). Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Beta-alanine receptor; G protein-coupled receptor MrgD; G-protein coupled receptor TGR7; mas-related G protein-coupled MRGD; Mas-related G protein-coupled receptor d; Mas-related G-protein coupled receptor member D; MAS-related G-protein coupled receptor, member D; MAS-related gene D; MAS-related GPR, member D; MRGD G protein-coupled receptor
基因别名: Gm499; Mgrd; MRGD; MRGPRD; TGR7
UniProt ID: (Human) Q8TDS7, (Rat) Q7TN41, (Mouse) Q91ZB8
Entrez Gene ID: (Human) 116512, (Rat) 293648, (Mouse) 211578
