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Osenses
MRGPRD Polyclonal Antibody
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产品信息
OSM00059W-100UL
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ Ig
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide from mouse MRGPRD conjugated to blue carrier protein was used as the antigen
偶联物
形式
Lyophilized
浓度
Conc. Not Determined
保存液
whole serum
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The antigen shares 81% identity with rat sequence.
Specificity of this antibody: MRGPRD.
靶标信息
May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i). Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Beta-alanine receptor; G protein-coupled receptor MrgD; G-protein coupled receptor TGR7; Mas-related G protein-coupled receptor d; Mas-related G-protein coupled receptor member D
基因别名: Gm499; Mgrd; MrgD; Mrgprd; TGR7
UniProt ID: (Mouse) Q91ZB8
Entrez Gene ID: (Mouse) 211578
