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Invitrogen
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The antibody detects endogenous levels of total MRPL10 protein.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 5q.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 39S ribosomal protein L10, mitochondrial; 39S ribosomal protein L8, mitochondrial; L10mt; L8mt; Large ribosomal subunit protein uL10m
基因别名: L10MT; MRP-L10; MRP-L8; MRPL10; MRPL8; RPML8
UniProt ID: (Human) Q7Z7H8
Entrez Gene ID: (Human) 124995