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Invitrogen
MRPL22 Polyclonal Antibody
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MRPL22 Antibody (PA5-109977) in WB
Western blot analysis of MRPL22 in extracts of various cell lines. Samples were incubated with MRPL22 Polyclonal antibody (Product # PA5-109977) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-109977
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 97-206 of human MRPL22 (NP_054899.2).
偶联物
形式
Liquid
浓度
1.78 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LAQLEFNDKK GAKIIKEVLL EAQDMAVRDH NVEFRSNLYI AESTSGRGQC LKRIRYHGRG RFGIMEKVYC HYFVKLVEGP PPPPEPPKTA VAHAKEYIQQ LRSRTIVHTL
靶标信息
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 39S ribosomal protein L22, mitochondrial; L22mt; Large ribosomal subunit protein uL22m; MRP-L22
基因别名: E030011D16Rik; HSPC158; MRP-L25; Mrpl22; Rpml25
UniProt ID: (Rat) P0C2C0, (Mouse) Q8BU88
Entrez Gene ID: (Rat) 287302, (Mouse) 216767
