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Invitrogen
MRPL40 Polyclonal Antibody
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MRPL40 Antibody (PA5-109982) in WB
Western blot analysis of MRPL40 in extracts of various cell lines. Samples were incubated with MRPL40 Polyclonal antibody (Product # PA5-109982) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-109982
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 45-206 of human MRPL40 (NP_0037672)
偶联物
形式
Liquid
浓度
0.7 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MRSEPLRKKK KVDPKKDQEA KERLKRKIRK LEKATQELIP IEDFITPLKF LDKARERPQV ELTFEETERR ALLLKKWSLY KQQERKMERD TIRAMLEAQQ EALEELQLES PKLHAEAIKR DPNLFPFEKE GPHYTPPIPN YQPPEGRYND ITKVYTQVEF KR
靶标信息
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 39S ribosomal protein L40, mitochondrial; L40mt; Large ribosomal subunit protein mL40; Nuclear localization signal-containing protein deleted in velocardiofacial syndrome; Up-regulated in metastasis
基因别名: L40mt; MRP-L22; MRP-L40; MRPL22; MRPL40; NLVCF; URIM
UniProt ID: (Human) Q9NQ50
Entrez Gene ID: (Human) 64976
